We recommend Forti5® as a natural hair growth supplement.
Forti5 is a nutritional supplement designed by world leading dermatologists based on the most advanced hair loss research currently available. It helps to restore and support thicker and faster growth of thinning hair through five key pathways:
• Supporting stimulation of hair growth
• Helping support prevention of hair loss
• Providing 5-Alpha Reductase inhibitors to help block DHT
• Delivering key antioxidants
• Supplying anti-inflammatory benefits
Reasons Why You May Be Suffering From Hair Loss
Androgenetic Alopecia (AGA)
AGA is the most common form of hair loss, affecting up to 80% of men and 50% of women in the course of their lives. Androgenetic alopecia is caused by a progressive reduction in the diameter, length and pigmentation of the hair. Hair thinning is limited to the frontal, temporal and vertex areas (androgen dependent scalp regions) and results from the effects of the testosterone metabolite dehydrotestosterone (DHT), known to cause hair loss, on androgen-sensitive hair follicles. Androgen sensitivity is genetically determined and depends on DHT production through the 5-alpha reductase enzyme.
5-Alpha Reductase
5-alpha reductase isoenzymes are responsible for converting free testosterone into DHT. There are 2 isoenzymes : type 1 and 2. In the scalp, type 1 is mainly located in the sebaceous gland and type 2 in the hair follicle. Inhibition of type 2 5-alpha reductase is an effective treatment of AGA. This is important because DHT may promote hair loss by preventing blood flow to the hair follicles.
Inflammation
Inflammation is commonly associated with androgenetic alopecia and other scalp disorders. The implication of microscopic follicular inflammation in the pathogenesis of AGA has emerged from several independent studies. Inflammatory cytokines induce telogen and can accelerate progression of androgenetic alopecia.
Oxidative Stress
Oxidative stress may be a pivotal mechanism contributing to hair graying and hair loss. This can be increased by multiple factors including smoking and UV Radiation, which are known to aggravate AGA. Scientific evidence supports the hypothesis that oxidative stress also plays a role in the aging process of the hair follicle. Reactive oxygen species are generated by a multitude of endogenous and environmental challenges. The body possesses endogenous defense mechanisms, such as antioxidant enzymes and non-enzymatic antioxidant molecules, protecting it from free radicals by reducing and neutralizing them. With age, the production of free radicals increases, while the endogenous defense mechanisms decrease. Anti-oxidants can then have an important role in the prevention and treatment of hair loss
Sex Hormone Binding Globulin (SHBG)
There is a clinically established inverse relationship between sex hormone binding globulin (SHBG) and androgenetic alopecia (AGA) in women. Increasing of the SHBG levels reduce bioavailability of sex hormones. Studies have shown low levels of SHBG to be associated with Male and Female Pattern Baldness.
